Vitamin C and Wound Healing

How It Works

Vitamin C promotes the healing of wounds and injuries through increasing production of collagen, antioxidant activity and enhancing immune cell function (MacKay & Miller, 2003).

Clinical studies found that vitamin C reduces the incidence of hip fractures in the elderly (Sahni, et al.,  2009), and complex regional pain syndrome following wrist fractures (Zollinger, et al., 2007).

Collagen and vitamin C are essential for new bone formation and repair. Vitamin C can accelerate the healing of ulcers and pressure sores (Taylor, et al., 1974).

High dose intravenous vitamin C given within 24 hours of receiving severe burns or trauma can reduce vitamin C deficiency, lipid peroxidation, resuscitation volume, oedema formation, respiratory dysfunction, incidence of organ failure, duration of mechanical ventilation, and time spent in the intensive care unit (Tanaka, et al., 2000; Nathens, et al., 2002).

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The information provided here is only for general reference and cannot replace personalised professional medical advice from a doctor. You are welcome to discuss any points during your consultation with our doctors.


  • MacKay D, Miller Al. (2003). Nutritional support for wound healing. Altern Med Rev. 8: 359-377.
  • Nathens AB, et al. (2002). Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg. 236: 814-822.
  • Sahni S, et al. (2009). Protective effect of total and supplemental vitamin C intake on the risk of hip fracture–a 17-year follow-up from the Framingham Osteoporosis Study. Osteoporos Int. 20: 1853-1861.
  • Tanaka H, et al. (2000). Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Arch Surg. 135: 326-331.
  • Taylor TV, et al. (1974). Ascorbic acid supplementation in the treatment of pressure-sores. Lancet. 2: 544-546.
  • Zollinger PE, et al. (2007). Can vitamin C prevent complex regional pain syndrome in patients with wrist fractures? A randomized, controlled, multicenter dose-response study. J Bone Joint Surg Am. 89: 1424-1431.